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Gene: Pdcd4 (programmed cell death 4) Mus musculus
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Symbol: Pdcd4
Name: programmed cell death 4
Description: Predicted to have RNA binding activity. Involved in cellular response to lipopolysaccharide; negative regulation of cytokine production involved in inflammatory response; and positive regulation of inflammatory response. Predicted to localize to cytosol and nucleus. Is expressed in several structures, including brain; early conceptus; epithelium; oocyte; and thymus primordium. Orthologous to human PDCD4 (programmed cell death 4); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D19Ucla1; Ma3; programmed cell death protein 4; protein MA-3; Tis; topoisomerase-inhibitor suppressed protein
Orthologs:
Homo sapiens (human) : PDCD4 (programmed cell death 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdcd4 (programmed cell death 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd4 (programmed cell death 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDCD4 (programmed cell death 4)
Canis lupus familiaris (dog) : PDCD4 (programmed cell death 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd4 (programmed cell death 4)
Sus scrofa (pig) : PDCD4 (programmed cell death 4)
Chlorocebus sabaeus (African green monkey) : PDCD4 (programmed cell death 4)
Heterocephalus glaber (naked mole-rat) : Pdcd4 (programmed cell death 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1953,892,231 - 53,929,860 (+)EnsemblGRCm38mm10GRCm38
GRCm381953,892,231 - 53,937,592 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371953,966,721 - 54,004,351 (+)NCBIGRCm37mm9NCBIm37
MGSCv361953,956,779 - 53,983,162 (+)NCBImm8
Celera1956,087,143 - 56,124,829 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1948.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdcd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732160
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.