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Gene: Pdcd4 (programmed cell death 4) Mus musculus
Symbol: Pdcd4
Name: programmed cell death 4
Description: Predicted to have RNA binding activity. Involved in cellular response to lipopolysaccharide; negative regulation of cytokine production involved in inflammatory response; and positive regulation of inflammatory response. Predicted to localize to cytosol and nucleus. Is expressed in several structures, including brain; early conceptus; epithelium; oocyte; and thymus primordium. Orthologous to human PDCD4 (programmed cell death 4); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D19Ucla1; Ma3; programmed cell death protein 4; protein MA-3; Tis; topoisomerase-inhibitor suppressed protein
Homo sapiens (human) : PDCD4 (programmed cell death 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdcd4 (programmed cell death 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd4 (programmed cell death 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDCD4 (programmed cell death 4)
Canis lupus familiaris (dog) : PDCD4 (programmed cell death 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd4 (programmed cell death 4)
Sus scrofa (pig) : PDCD4 (programmed cell death 4)
Chlorocebus sabaeus (African green monkey) : PDCD4 (programmed cell death 4)
Heterocephalus glaber (naked mole-rat) : Pdcd4 (programmed cell death 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1953,892,231 - 53,929,860 (+)EnsemblGRCm38mm10GRCm38
GRCm381953,892,231 - 53,937,592 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371953,966,721 - 54,004,351 (+)NCBIGRCm37mm9NCBIm37
MGSCv361953,956,779 - 53,983,162 (+)NCBImm8
Celera1956,087,143 - 56,124,829 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1948.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pdcd4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732160
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.