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Gene: SCN4A (sodium voltage-gated channel alpha subunit 4) Homo sapiens
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Symbol: SCN4A
Name: sodium voltage-gated channel alpha subunit 4
Description: Exhibits voltage-gated sodium channel activity. Involved in regulation of skeletal muscle contraction by action potential and sodium ion transmembrane transport. Localizes to voltage-gated sodium channel complex. Implicated in congenital myasthenic syndrome 16; hyperkalemic periodic paralysis; and paramyotonia congenita of Von Eulenburg.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMS16; CTC-264K15.6; HOKPP2; HYKPP; HYPP; Na(V)1.4; NAC1A; Nav1.4; skeletal muscle sodium channel alpha subunit; skeletal muscle voltage-dependent sodium channel type IV alpha subunit; SkM1; sodium channel protein skeletal muscle subunit alpha; sodium channel protein type 4 subunit alpha; sodium channel protein type IV subunit alpha; sodium channel, voltage gated, type IV alpha subunit; sodium channel, voltage-gated, type IV, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.4
Orthologs:
Mus musculus (house mouse) : Scn4a (sodium channel, voltage-gated, type IV, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scn4a (sodium voltage-gated channel alpha subunit 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn4a (sodium voltage-gated channel alpha subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN4A (sodium voltage-gated channel alpha subunit 4)
Canis lupus familiaris (dog) : SCN4A (sodium voltage-gated channel alpha subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn4a (sodium voltage-gated channel alpha subunit 4)
Sus scrofa (pig) : SCN4A (sodium voltage-gated channel alpha subunit 4)
Chlorocebus sabaeus (African green monkey) : SCN4A (sodium voltage-gated channel alpha subunit 4)
Heterocephalus glaber (naked mole-rat) : Scn4a (sodium voltage-gated channel alpha subunit 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1763,938,554 - 63,972,918 (-)EnsemblGRCh38hg38GRCh38
GRCh381763,938,554 - 63,972,918 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371762,015,914 - 62,066,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,369,646 - 59,404,010 (-)NCBINCBI36hg18NCBI36
Build 341759,369,645 - 59,404,010NCBI
Celera1756,403,975 - 56,438,354 (-)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,383,629 - 57,417,946 (-)NCBIHuRef
CHM1_11762,079,833 - 62,114,196 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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