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Gene: RENBP (renin binding protein) Homo sapiens
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Symbol: RENBP
Name: renin binding protein
Description: The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; N-acylglucosamine 2-epimerase; RBP; renin-binding protein; RNBP
Orthologs:
Mus musculus (house mouse) : Renbp (renin binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Renbp (renin binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Renbp (renin binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : RENBP (renin binding protein)
Canis lupus familiaris (dog) : RENBP (renin binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Renbp (renin binding protein)
Sus scrofa (pig) : RENBP (renin binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,935,263 - 153,944,780 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,200,722 - 153,210,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,853,917 - 152,863,426 (-)NCBINCBI36hg18NCBI36
Build 34X152,721,569 - 152,731,079NCBI
CeleraX153,434,439 - 153,443,945 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX141,853,485 - 141,862,600 (-)NCBIHuRef
CHM1_1X153,075,217 - 153,084,644 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on RENBP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732186
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.