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Gene: RENBP (renin binding protein) Homo sapiens
Symbol: RENBP
Name: renin binding protein
Description: The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; N-acylglucosamine 2-epimerase; RBP; renin-binding protein; RNBP
Mus musculus (house mouse) : Renbp (renin binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Renbp (renin binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Renbp (renin binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : RENBP (renin binding protein)
Canis lupus familiaris (dog) : RENBP (renin binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Renbp (renin binding protein)
Sus scrofa (pig) : RENBP (renin binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X153,935,263 - 153,944,780 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,200,722 - 153,210,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,853,917 - 152,863,426 (-)NCBINCBI36hg18NCBI36
Build 34X152,721,569 - 152,731,079NCBI
CeleraX153,434,439 - 153,443,945 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX141,853,485 - 141,862,600 (-)NCBIHuRef
CHM1_1X153,075,217 - 153,084,644 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RENBP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732186
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.