Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MYO7A (myosin VIIA) Homo sapiens
Analyze
Symbol: MYO7A
Name: myosin VIIA
CRRD ID: 732206
Description: Exhibits calmodulin binding activity; cytoskeletal protein binding activity; and microfilament motor activity. Involved in several processes, including equilibrioception; sensory perception of sound; and visual perception. Localizes to several cellular components, including lysosomal membrane; photoreceptor inner segment; and photoreceptor outer segment. Implicated in Leber congenital amaurosis; Usher syndrome (multiple); auditory system disease (multiple); and congenital nystagmus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deafness, autosomal dominant 11; deafness, autosomal recessive 2; DFNA11; DFNB2; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)); myosin-VIIa; MYOVIIA; MYU7A; NSRD2; unconventional myosin-VIIa; USH1B
Orthologs:
Mus musculus (house mouse) : Myo7a (myosin VIIA)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myo7a (myosin VIIA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo7a (myosin VIIA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO7A (myosin VIIA)
Canis lupus familiaris (dog) : MYO7A (myosin VIIA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo7a (myosin VIIA)
Sus scrofa (pig) : MYO7A (myosin VIIA)
Chlorocebus sabaeus (African green monkey) : MYO7A (myosin VIIA)
Heterocephalus glaber (naked mole-rat) : Myo7a (myosin VIIA)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1177,128,246 - 77,215,241 (+)EnsemblGRCh38hg38GRCh38
GRCh381177,128,192 - 77,215,241 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371176,839,302 - 76,926,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,516,964 - 76,603,932 (+)NCBINCBI36hg18NCBI36
Build 341176,516,957 - 76,603,931NCBI
Celera1174,146,794 - 74,233,913 (+)NCBI
Cytogenetic Map11q13.5NCBI
HuRef1173,136,682 - 73,224,253 (+)NCBIHuRef
CHM1_11176,722,561 - 76,809,502 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers