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Gene: Myo7a (myosin VIIA) Mus musculus
Symbol: Myo7a
Name: myosin VIIA
Description: Exhibits protein domain specific binding activity. Involved in several processes, including animal organ morphogenesis; phagolysosome assembly; and pigment granule transport. Localizes to several cellular components, including the melanosome; photoreceptor connecting cilium; and stereocilium base. Used to study Usher syndrome type 1 and autosomal recessive nonsyndromic deafness 2. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Usher syndrome (multiple); auditory system disease (multiple); and congenital nystagmus. Is expressed in central nervous system; inner ear; olfactory epithelium; and retina. Orthologous to human MYO7A (myosin VIIA); PARTICIPATES IN auditory mechanotransduction pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hdb; motor protein; Myo7; myosin-VIIa; nmf371; polka; sh-1; sh1; shaker 1; unconventional myosin-VIIa; USH1B
Homo sapiens (human) : MYO7A (myosin VIIA)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myo7a (myosin VIIA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo7a (myosin VIIA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO7A (myosin VIIA)
Canis lupus familiaris (dog) : MYO7A (myosin VIIA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo7a (myosin VIIA)
Sus scrofa (pig) : MYO7A (myosin VIIA)
Chlorocebus sabaeus (green monkey) : MYO7A (myosin VIIA)
Heterocephalus glaber (naked mole-rat) : Myo7a (myosin VIIA)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl798,051,060 - 98,119,524 (-)Ensembl
GRCm38798,051,054 - 98,119,522 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377105,199,570 - 105,268,003 (-)NCBIGRCm37mm9NCBIm37
MGSCv36797,926,593 - 97,992,926 (-)NCBImm8
Celera798,371,622 - 98,440,211 (-)NCBICelera
Cytogenetic Map7 E1NCBI
cM Map753.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Myo7a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732207
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.