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Gene: ABCG5 (ATP binding cassette subfamily G member 5) Homo sapiens
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Symbol: ABCG5
Name: ATP binding cassette subfamily G member 5
Description: Exhibits ATPase-coupled transmembrane transporter activity and protein heterodimerization activity. Contributes to ATP binding activity; ATPase activity; and cholesterol transfer activity. Involved in several processes, including cholesterol efflux; cholesterol homeostasis; and negative regulation of intestinal lipid absorption. Localizes to ATP-binding activity cassette (ABC) transporter complex; apical plasma membrane; and receptor complex. Implicated in arteriosclerosis and sitosterolemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-binding cassette sub-family G member 5; ATP-binding cassette, sub-family G (WHITE), member 5; ATP-binding cassette, subfamily G, member 5; sterolin 1; sterolin-1; STSL; STSL2
Orthologs:
Mus musculus (house mouse) : Abcg5 (ATP binding cassette subfamily G member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcg5 (ATP binding cassette subfamily G member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcg5 (ATP binding cassette subfamily G member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCG5 (ATP binding cassette subfamily G member 5)
Canis lupus familiaris (dog) : ABCG5 (ATP binding cassette subfamily G member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcg5 (ATP binding cassette subfamily G member 5)
Sus scrofa (pig) : ABCG5 (ATP binding cassette subfamily G member 5)
Chlorocebus sabaeus (African green monkey) : ABCG5 (ATP binding cassette subfamily G member 5)
Heterocephalus glaber (naked mole-rat) : Abcg5 (ATP binding cassette subfamily G member 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl243,812,472 - 43,838,865 (-)EnsemblGRCh38hg38GRCh38
GRCh38243,806,154 - 43,838,840 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37244,039,611 - 44,066,039 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,893,115 - 43,919,462 (-)NCBINCBI36hg18NCBI36
Build 34243,951,261 - 43,977,609NCBI
Celera243,878,347 - 43,904,690 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef243,776,307 - 43,802,654 (-)NCBIHuRef
CHM1_1243,969,007 - 43,995,357 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ABCG5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732219
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.