Gene: GSTP1 (glutathione S-transferase pi 1) Homo sapiens
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Symbol: GSTP1
Name: glutathione S-transferase pi 1
Description: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deafness, X-linked 7; DFN7; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-transferase P; glutathione S-transferase pi; glutathione s-transferase, pi 2; GST class-pi; GST3; GSTP; GSTP1-1; HEL-S-22; PI
Orthologs:
Mus musculus (house mouse) : Gstp1 (glutathione S-transferase, pi 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gstp1 (glutathione S-transferase pi 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gstp1 (glutathione S-transferase pi 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GSTP1 (glutathione S-transferase pi 1)
Canis lupus familiaris (dog) : GSTP1 (glutathione S-transferase pi 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gstp1 (glutathione S-transferase pi 1)
Sus scrofa (pig) : LOC100739163 (glutathione S-transferase P-like)
more info ...
Related Pseudogenes: GSTP1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,583,595 - 67,586,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371167,351,066 - 67,354,125 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,107,862 - 67,110,699 (+)NCBINCBI36hg18NCBI36
Build 341167,107,861 - 67,110,699NCBI
Celera1164,685,527 - 64,688,585 (+)NCBI
Cytogenetic Map11q13.2NCBI
HuRef1163,680,236 - 63,683,230 (+)NCBIHuRef
CHM1_11167,234,118 - 67,237,177 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GSTP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732257
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.