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Gene: Cdc37 (cell division cycle 37) Mus musculus
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Symbol: Cdc37
Name: cell division cycle 37
Description: Exhibits Hsp90 protein binding activity and kinase binding activity. Contributes to protein kinase regulator activity. Involved in positive regulation of mitophagy in response to mitochondrial depolarization; posttranscriptional regulation of gene expression; and regulation of protein kinase activity. Localizes to the HSP90-CDC37 chaperone complex and cytosol. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Orthologous to human CDC37 (cell division cycle 37); PARTICIPATES IN protein kinase C (PKC) signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; carbon nanotube.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; hsp90 co-chaperone Cdc37; p50; p50Cdc37
Orthologs:
Homo sapiens (human) : CDC37 (cell division cycle 37)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdc37 (cell division cycle 37)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc37 (cell division cycle 37)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC37 (cell division cycle 37)
Canis lupus familiaris (dog) : CDC37 (cell division cycle 37)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc37 (cell division cycle 37)
Sus scrofa (pig) : CDC37 (cell division cycle 37)
Chlorocebus sabaeus (African green monkey) : CDC37 (cell division cycle 37)
Heterocephalus glaber (naked mole-rat) : Cdc37 (cell division cycle 37)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl921,133,222 - 21,149,982 (-)EnsemblGRCm38mm10GRCm38
GRCm38921,138,541 - 21,149,981 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37920,942,985 - 20,954,350 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,888,943 - 20,900,308 (-)NCBImm8
Celera918,407,255 - 18,418,620 (-)NCBICelera
Cytogenetic Map9A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Cell Lines
Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Cdc37
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732259
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.