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Gene: GFRA2 (GDNF family receptor alpha 2) Homo sapiens
Symbol: GFRA2
Name: GDNF family receptor alpha 2
Description: Predicted to have glial cell-derived neurotrophic factor receptor activity. Predicted to be involved in nervous system development and positive regulation of peptidyl-serine phosphorylation of STAT protein. Predicted to localize to external side of plasma membrane and receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GDNF family receptor alpha-2; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GDNFRB; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; neurturin receptor alpha; NRTNR-ALPHA; NTNR-alpha; NTNRA; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta related neurotrophic factor receptor 2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2
Mus musculus (house mouse) : Gfra2 (glial cell line derived neurotrophic factor family receptor alpha 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gfra2 (GDNF family receptor alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfra2 (GDNF family receptor alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GFRA2 (GDNF family receptor alpha 2)
Canis lupus familiaris (dog) : GFRA2 (GDNF family receptor alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfra2 (GDNF family receptor alpha 2)
Sus scrofa (pig) : GFRA2 (GDNF family receptor alpha 2)
Chlorocebus sabaeus (African green monkey) : GFRA2 (GDNF family receptor alpha 2)
Heterocephalus glaber (naked mole-rat) : Gfra2 (GDNF family receptor alpha 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl821,690,398 - 21,812,357 (-)EnsemblGRCh38hg38GRCh38
GRCh38821,690,398 - 21,789,296 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37821,549,530 - 21,672,392 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36821,688,430 - 21,702,292 (-)NCBINCBI36hg18NCBI36
Build 36821,593,810 - 21,652,734 (-)NCBINCBI36hg18NCBI36
Build 34821,688,428 - 21,702,292NCBI
Celera820,513,992 - 20,608,606 (-)NCBI
Cytogenetic Map8p21.3NCBI
HuRef820,092,831 - 20,150,935 (-)NCBIHuRef
HuRef820,169,214 - 20,189,376 (-)NCBIHuRef
CHM1_1821,751,217 - 21,848,063 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GFRA2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732295
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.