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Gene: Ncoa3 (nuclear receptor coactivator 3) Mus musculus
Symbol: Ncoa3
Name: nuclear receptor coactivator 3
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulator recruiting activity; and transcription coactivator activity. Involved in several processes, including growth; mammary gland branching involved in thelarche; and reproductive structure development. Localizes to the RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human NCOA3 (nuclear receptor coactivator 3); PARTICIPATES IN androgen signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010305B15Rik; Actr; AIB-1; Aib1; amplified in breast cancer-1 protein homolog; AW321064; bHLHe42; CBP-interacting protein; KAT13B; NCoA-3; p/Cip; pCip; RAC-3; Rac3; receptor-associated coactivator 3; RIKEN cDNA 2010305B15 gene; SRC-3; Src3; steroid receptor coactivator protein 3; thyroid hormone receptor activator molecule 1; Tram-1; Tram1
Homo sapiens (human) : NCOA3 (nuclear receptor coactivator 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncoa3 (nuclear receptor coactivator 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa3 (nuclear receptor coactivator 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA3 (nuclear receptor coactivator 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa3 (nuclear receptor coactivator 3)
Sus scrofa (pig) : NCOA3 (nuclear receptor coactivator 3)
Chlorocebus sabaeus (African green monkey) : NCOA3 (nuclear receptor coactivator 3)
Heterocephalus glaber (naked mole-rat) : Ncoa3 (nuclear receptor coactivator 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2165,992,636 - 166,073,242 (+)Ensembl
GRCm382165,992,616 - 166,073,242 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372165,818,137 - 165,898,742 (+)NCBIGRCm37mm9NCBIm37
MGSCv362165,726,090 - 165,761,651 (+)NCBImm8
Celera2171,928,977 - 172,011,677 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ncoa3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732296
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.