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Gene: KAT5 (lysine acetyltransferase 5) Homo sapiens
Symbol: KAT5
Name: lysine acetyltransferase 5
Description: Exhibits histone acetyltransferase activity; repressing transcription factor binding activity; and transcription coactivator activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; cellular protein metabolic process; and positive regulation of cellular metabolic process. Localizes to the Piccolo NuA4 histone acetyltransferase complex; Swr1 complex; and nucleolus. Biomarker of breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 60 kDa Tat-interactive protein; cPLA(2)-interacting protein; cPLA2; cPLA2 interacting protein; ESA1; histone acetyltransferase HTATIP; histone acetyltransferase KAT5; HIV-1 Tat interacting protein, 60kDa; hiv-1 tat interactive protein, 60 kd; HIV-1 Tat interactive protein, 60kDa; HTATIP; HTATIP1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; PLIP; Tat interacting protein, 60kDa; TIP; TIP60; ZC2HC5
Mus musculus (house mouse) : Kat5 (K(lysine) acetyltransferase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kat5 (lysine acetyltransferase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kat5 (lysine acetyltransferase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : KAT5 (lysine acetyltransferase 5)
Canis lupus familiaris (dog) : KAT5 (lysine acetyltransferase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kat5 (lysine acetyltransferase 5)
Sus scrofa (pig) : KAT5 (lysine acetyltransferase 5)
Chlorocebus sabaeus (African green monkey) : KAT5 (lysine acetyltransferase 5)
Heterocephalus glaber (naked mole-rat) : Kat5 (lysine acetyltransferase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1165,711,996 - 65,719,604 (+)EnsemblGRCh38hg38GRCh38
GRCh381165,712,018 - 65,719,604 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371165,479,473 - 65,487,077 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,236,065 - 65,243,651 (+)NCBINCBI36hg18NCBI36
Build 341165,236,064 - 65,243,650NCBI
Celera1162,806,503 - 62,814,088 (+)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,806,327 - 61,813,930 (+)NCBIHuRef
CHM1_11165,363,389 - 65,370,993 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KAT5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732354
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.