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Gene: RGS2 (regulator of G protein signaling 2) Homo sapiens
Symbol: RGS2
Name: regulator of G protein signaling 2
Description: Exhibits G-protein alpha-subunit binding activity and GTPase activator activity. Involved in regulation of G protein-coupled receptor signaling pathway. Localizes to cytosol; nucleus; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; G0S8; regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; regulator of g-protein signaling protein 2
Mus musculus (house mouse) : Rgs2 (regulator of G-protein signaling 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rgs2 (regulator of G-protein signaling 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs2 (regulator of G protein signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS2 (regulator of G protein signaling 2)
Canis lupus familiaris (dog) : RGS2 (regulator of G protein signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs2 (regulator of G protein signaling 2)
Sus scrofa (pig) : RGS2 (regulator of G protein signaling 2)
Chlorocebus sabaeus (African green monkey) : RGS2 (regulator of G protein signaling 2)
Heterocephalus glaber (naked mole-rat) : Rgs2 (regulator of G protein signaling 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1192,809,039 - 192,812,275 (+)EnsemblGRCh38hg38GRCh38
GRCh381192,809,039 - 192,812,275 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371192,778,169 - 192,781,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,044,794 - 191,048,026 (+)NCBINCBI36hg18NCBI36
Build 341189,509,827 - 189,513,060NCBI
Celera1165,887,766 - 165,891,002 (+)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,013,977 - 164,017,213 (+)NCBIHuRef
CHM1_11194,199,847 - 194,203,081 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RGS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732360
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.