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Gene: NTF3 (neurotrophin 3) Homo sapiens
Symbol: NTF3
Name: neurotrophin 3
Description: Exhibits chemoattractant activity and growth factor activity. Involved in several processes, including activation of GTPase activity; positive regulation of cellular component organization; and regulation of protein phosphorylation. Predicted to localize to several cellular components, including the axon; dendrite; and synaptic vesicle. Implicated in Alzheimer's disease and asthma. Biomarker of chronic obstructive pulmonary disease; hydrocephalus; and pulmonary sarcoidosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HDNF; MGC129711; nerve growth factor 2; neurotrophic factor; neurotrophin-3; NGF-2; NGF2; NT-3; NT3
Mus musculus (house mouse) : Ntf3 (neurotrophin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ntf3 (neurotrophin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ntf3 (neurotrophin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NTF3 (neurotrophin 3)
Canis lupus familiaris (dog) : NTF3 (neurotrophin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ntf3 (neurotrophin 3)
Sus scrofa (pig) : NTF3 (neurotrophin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38125,432,108 - 5,495,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37125,541,280 - 5,604,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,411,541 - 5,474,726 (+)NCBINCBI36hg18NCBI36
Build 34125,473,526 - 5,474,725NCBI
Celera127,162,184 - 7,225,194 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef125,455,606 - 5,458,036 (+)NCBIHuRef
CHM1_1125,540,527 - 5,604,287 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NTF3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732368
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.