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Gene: NTF3 (neurotrophin 3) Homo sapiens
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Symbol: NTF3
Name: neurotrophin 3
Description: Exhibits chemoattractant activity and growth factor activity. Involved in several processes, including activation of GTPase activity; positive regulation of cellular component organization; and regulation of protein phosphorylation. Predicted to localize to several cellular components, including the axon; dendrite; and synaptic vesicle. Implicated in Alzheimer's disease and asthma. Biomarker of chronic obstructive pulmonary disease; hydrocephalus; and pulmonary sarcoidosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HDNF; MGC129711; nerve growth factor 2; neurotrophic factor; neurotrophin-3; NGF-2; NGF2; NT-3; NT3
Orthologs:
Mus musculus (house mouse) : Ntf3 (neurotrophin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ntf3 (neurotrophin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ntf3 (neurotrophin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NTF3 (neurotrophin 3)
Canis lupus familiaris (dog) : NTF3 (neurotrophin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ntf3 (neurotrophin 3)
Sus scrofa (pig) : NTF3 (neurotrophin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,432,108 - 5,495,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37125,541,280 - 5,604,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,411,541 - 5,474,726 (+)NCBINCBI36hg18NCBI36
Build 34125,473,526 - 5,474,725NCBI
Celera127,162,184 - 7,225,194 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef125,455,606 - 5,458,036 (+)NCBIHuRef
CHM1_1125,540,527 - 5,604,287 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NTF3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732368
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.