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Gene: Trib3 (tribbles pseudokinase 3) Mus musculus
Symbol: Trib3
Name: tribbles pseudokinase 3
Description: Exhibits enzyme binding activity; transcription corepressor activity; and ubiquitin-protein transferase regulator activity. Involved in several processes, including negative regulation of fat cell differentiation; negative regulation of fatty acid biosynthetic process; and regulation of protein modification process. Localizes to the nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart; and retina. Orthologous to human TRIB3 (tribbles pseudokinase 3); INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (R)-lipoic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ifld2; induced in fatty liver dystrophy 2; neuronal cell death-inducible putative kinase; Nipk; SINK; SKIP3; TRB-3; Trb3; tribbles homolog 3
Homo sapiens (human) : TRIB3 (tribbles pseudokinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Trib3 (tribbles pseudokinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trib3 (tribbles pseudokinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIB3 (tribbles pseudokinase 3)
Canis lupus familiaris (dog) : TRIB3 (tribbles pseudokinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trib3 (tribbles pseudokinase 3)
Sus scrofa (pig) : TRIB3 (tribbles pseudokinase 3)
Chlorocebus sabaeus (African green monkey) : TRIB3 (tribbles pseudokinase 3)
Heterocephalus glaber (naked mole-rat) : Trib3 (tribbles pseudokinase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2152,337,422 - 152,344,032 (-)EnsemblGRCm38mm10GRCm38
GRCm382152,337,425 - 152,344,060 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372152,163,161 - 152,169,796 (-)NCBIGRCm37mm9NCBIm37
MGSCv362152,028,863 - 152,035,473 (-)NCBImm8
Celera2158,151,551 - 158,158,172 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Trib3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732371
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.