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Gene: TNNT2 (troponin T2, cardiac type) Homo sapiens
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Symbol: TNNT2
Name: troponin T2, cardiac type
Description: Exhibits cytoskeletal protein binding activity. Contributes to ATPase activity. Involved in several processes, including muscle filament sliding; regulation of ATPase activity; and ventricular cardiac muscle tissue morphogenesis. Localizes to the cardiac Troponin complex and cardiac myofibril. Implicated in intrinsic cardiomyopathy (multiple). Biomarker of myocardial infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cardiac muscle troponin T; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; LVNC6; MGC3889; RCM3; TnTC; troponin T type 2 (cardiac); troponin T, cardiac muscle; troponin t2; troponin T2, cardiac; truncated cardiac troponin T
Orthologs:
Mus musculus (house mouse) : Tnnt2 (troponin T2, cardiac)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnnt2 (troponin T2, cardiac type)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnnt2 (troponin T2, cardiac type)
Pan paniscus (bonobo/pygmy chimpanzee) : TNNT2 (troponin T2, cardiac type)
Canis lupus familiaris (dog) : TNNT2 (troponin T2, cardiac type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnnt2 (troponin T2, cardiac type)
Sus scrofa (pig) : TNNT2 (troponin T2, cardiac type)
Chlorocebus sabaeus (African green monkey) : TNNT2 (troponin T2, cardiac type)
Heterocephalus glaber (naked mole-rat) : Tnnt2 (troponin T2, cardiac type)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1201,359,008 - 201,377,764 (-)EnsemblGRCh38hg38GRCh38
GRCh381201,359,014 - 201,377,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371201,328,136 - 201,346,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,594,765 - 199,613,428 (-)NCBINCBI36hg18NCBI36
Build 341198,059,798 - 198,078,462NCBI
Celera1174,451,992 - 174,470,656 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1172,494,387 - 172,513,074 (-)NCBIHuRef
CHM1_11202,750,309 - 202,768,995 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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