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Gene: Myh9 (myosin, heavy polypeptide 9, non-muscle) Mus musculus
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Symbol: Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Description: Exhibits protein domain specific binding activity. Involved in several processes, including establishment of T cell polarity; microtubule cytoskeleton organization; and negative regulation of actin filament severing. Localizes to several cellular components, including the brush border; cytoskeleton; and uropod. Colocalizes with several cellular components, including the focal adhesion; immunological synapse; and neuromuscular junction. Used to study MYH-9 related disease. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal failure; and proteinuria. Is expressed in several structures, including alimentary system; future spinal cord; heart and pericardium; mesenchyme derived from neural crest; and sensory organ. Orthologous to human MYH9 (myosin heavy chain 9); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C80049; cellular myosin heavy chain, type A; D0Jmb2; E030044M24Rik; flectin; Fltn; Myhn-1; Myhn1; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin-9; NMHC II-A; NMHCIIA; NMMHC II-a; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; TU72.6
Orthologs:
Homo sapiens (human) : MYH9 (myosin heavy chain 9)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myh9 (myosin, heavy chain 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh9 (myosin heavy chain 9)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH9 (myosin heavy chain 9)
Canis lupus familiaris (dog) : MYH9 (myosin heavy chain 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh9 (myosin heavy chain 9)
Sus scrofa (pig) : MYH9 (myosin heavy chain 9)
Chlorocebus sabaeus (African green monkey) : MYH9 (myosin heavy chain 9)
Heterocephalus glaber (naked mole-rat) : Myh9 (myosin heavy chain 9)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1577,760,587 - 77,842,175 (-)EnsemblGRCm38mm10GRCm38
GRCm381577,760,585 - 77,842,175 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371577,591,019 - 77,672,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv361577,587,843 - 77,669,360 (-)NCBImm8
Celera1579,227,040 - 79,308,545 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1536.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myh9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732402
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.