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Gene: Myh9 (myosin, heavy polypeptide 9, non-muscle) Mus musculus
Symbol: Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Description: Exhibits protein domain specific binding activity. Involved in several processes, including establishment of T cell polarity; microtubule cytoskeleton organization; and negative regulation of actin filament severing. Localizes to several cellular components, including the brush border; cytoskeleton; and uropod. Colocalizes with several cellular components, including the focal adhesion; immunological synapse; and neuromuscular junction. Used to study MYH-9 related disease. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal failure; and proteinuria. Is expressed in several structures, including alimentary system; future spinal cord; heart and pericardium; mesenchyme derived from neural crest; and sensory organ. Orthologous to human MYH9 (myosin heavy chain 9); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C80049; cellular myosin heavy chain, type A; D0Jmb2; E030044M24Rik; flectin; Fltn; Myhn-1; Myhn1; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin-9; NMHC II-A; NMHCIIA; NMMHC II-a; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; TU72.6
Homo sapiens (human) : MYH9 (myosin heavy chain 9)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myh9 (myosin, heavy chain 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh9 (myosin heavy chain 9)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH9 (myosin heavy chain 9)
Canis lupus familiaris (dog) : MYH9 (myosin heavy chain 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh9 (myosin heavy chain 9)
Sus scrofa (pig) : MYH9 (myosin heavy chain 9)
Chlorocebus sabaeus (African green monkey) : MYH9 (myosin heavy chain 9)
Heterocephalus glaber (naked mole-rat) : Myh9 (myosin heavy chain 9)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1577,760,587 - 77,842,175 (-)EnsemblGRCm38mm10GRCm38
GRCm381577,760,585 - 77,842,175 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371577,591,019 - 77,672,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv361577,587,843 - 77,669,360 (-)NCBImm8
Celera1579,227,040 - 79,308,545 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1536.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Myh9
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732402
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.