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Gene: LIMK1 (LIM domain kinase 1) Homo sapiens
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Symbol: LIMK1
Name: LIM domain kinase 1
Description: Exhibits heat shock protein binding activity and protein serine/threonine kinase activity. Involved in negative regulation of ubiquitin-protein transferase activity; positive regulation of actin filament bundle assembly; and protein phosphorylation. Localizes to the cytosol and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LIM motif-containing protein kinase; lim motif-containing protein kinase 1; LIMK; LIMK-1
Orthologs:
Mus musculus (house mouse) : Limk1 (LIM-domain containing, protein kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Limk1 (LIM domain kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Limk1 (LIM domain kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMK1 (LIM domain kinase 1)
Canis lupus familiaris (dog) : LIMK1 (LIM domain kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Limk1 (LIM domain kinase 1)
Sus scrofa (pig) : LIMK1 (LIM domain kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,083,804 - 74,122,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,498,107 - 73,536,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,136,092 - 73,174,790 (+)NCBINCBI36hg18NCBI36
Build 34772,942,806 - 72,981,505NCBI
Celera768,977,591 - 69,016,280 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,382,814 - 69,418,976 (+)NCBIHuRef
CHM1_1773,643,562 - 73,682,183 (+)NCBICHM1_1
CRA_TCAGchr7v2772,831,179 - 72,869,927 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LIMK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732406
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.