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Gene: LIMK1 (LIM domain kinase 1) Homo sapiens
Symbol: LIMK1
Name: LIM domain kinase 1
Description: Exhibits heat shock protein binding activity and protein serine/threonine kinase activity. Involved in negative regulation of ubiquitin-protein transferase activity; positive regulation of actin filament bundle assembly; and protein phosphorylation. Localizes to the cytosol and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LIM motif-containing protein kinase; lim motif-containing protein kinase 1; LIMK; LIMK-1
Mus musculus (house mouse) : Limk1 (LIM-domain containing, protein kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Limk1 (LIM domain kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Limk1 (LIM domain kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMK1 (LIM domain kinase 1)
Canis lupus familiaris (dog) : LIMK1 (LIM domain kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Limk1 (LIM domain kinase 1)
Sus scrofa (pig) : LIMK1 (LIM domain kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38774,083,804 - 74,122,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,498,107 - 73,536,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,136,092 - 73,174,790 (+)NCBINCBI36hg18NCBI36
Build 34772,942,806 - 72,981,505NCBI
Celera768,977,591 - 69,016,280 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,382,814 - 69,418,976 (+)NCBIHuRef
CHM1_1773,643,562 - 73,682,183 (+)NCBICHM1_1
CRA_TCAGchr7v2772,831,179 - 72,869,927 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LIMK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732406
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.