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Gene: PLCB2 (phospholipase C beta 2) Homo sapiens
Symbol: PLCB2
Name: phospholipase C beta 2
Description: Exhibits phosphatidylinositol phospholipase C activity. Predicted to be involved in inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Predicted to localize to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; FLJ38135; phosphoinositide phospholipase C-beta-2; phospholipase C, beta 2; phospholipase C-beta-2; PLC-beta-2
Mus musculus (house mouse) : Plcb2 (phospholipase C, beta 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcb2 (phospholipase C, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb2 (phospholipase C beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB2 (phospholipase C beta 2)
Canis lupus familiaris (dog) : PLCB2 (phospholipase C beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb2 (phospholipase C beta 2)
Sus scrofa (pig) : PLCB2 (phospholipase C beta 2)
Chlorocebus sabaeus (African green monkey) : PLCB2 (phospholipase C beta 2)
Heterocephalus glaber (naked mole-rat) : Plcb2 (phospholipase C beta 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1540,278,176 - 40,307,935 (-)EnsemblGRCh38hg38GRCh38
GRCh381540,285,496 - 40,307,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371540,576,461 - 40,600,174 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,367,390 - 38,387,466 (-)NCBINCBI36hg18NCBI36
Build 341538,367,401 - 38,387,330NCBI
Celera1517,346,090 - 17,366,157 (-)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1517,423,058 - 17,443,532 (-)NCBIHuRef
CHM1_11540,700,041 - 40,720,115 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PLCB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732409
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.