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Gene: Lfng (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) Mus musculus
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Symbol: Lfng
Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Description: Exhibits O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in several processes, including anterior/posterior pattern specification; lymphocyte differentiation; and regulation of Notch signaling pathway. Predicted to localize to integral component of Golgi membrane. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; inner ear; and paraxial mesenchyme. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase); PARTICIPATES IN Notch signaling pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW061165; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; lunatic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl5140,607,320 - 140,615,545 (+)EnsemblGRCm38mm10GRCm38
GRCm385140,607,341 - 140,615,545 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375141,083,295 - 141,091,499 (+)NCBIGRCm37mm9NCBIm37
MGSCv365140,859,841 - 140,866,960 (+)NCBImm8
Celera5137,667,846 - 137,675,959 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map579.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lfng
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732418
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.