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Gene: CHI3L1 (chitinase 3 like 1) Homo sapiens
Symbol: CHI3L1
Name: chitinase 3 like 1
Description: Exhibits chitin binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; response to interleukin-1; and response to interleukin-6. Localizes to the extracellular space. Implicated in asthma and schizophrenia. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); hematologic cancer (multiple); lung disease (multiple); and reproductive organ cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 39 kDa synovial protein; ASRT7; cartilage glycoprotein 39; CGP-39; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-3-like protein 1; DKFZp686N19119; FLJ38139; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YK-40; YKL-40; YKL40; YYL-40
Mus musculus (house mouse) : Chil1 (chitinase-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chi3l1 (chitinase 3 like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chi3l1 (chitinase 3 like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CHI3L1 (chitinase 3 like 1)
Canis lupus familiaris (dog) : CHI3L1 (chitinase 3 like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chi3l1 (chitinase 3 like 1)
Sus scrofa (pig) : CHI3L1 (chitinase 3 like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381203,178,931 - 203,186,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,148,059 - 203,155,978 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,414,682 - 201,422,545 (-)NCBINCBI36hg18NCBI36
Build 341199,879,586 - 199,887,534NCBI
Celera1176,277,300 - 176,285,163 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,313,188 - 174,321,051 (-)NCBIHuRef
CHM1_11204,570,380 - 204,578,243 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHI3L1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732419
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.