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Gene: Smpd2 (sphingomyelin phosphodiesterase 2, neutral) Mus musculus
Symbol: Smpd2
Name: sphingomyelin phosphodiesterase 2, neutral
Description: Exhibits sphingomyelin phosphodiesterase activity. Involved in sphingomyelin catabolic process. Predicted to localize to caveola. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SMPD2 (sphingomyelin phosphodiesterase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW108287; lyso-PAF-PLC; lyso-platelet-activating factor-phospholipase C; N-SMase; neutral sphingomyelinase 1; nSMase; nSMase1; sphingomyelin phosphodiesterase 2
Homo sapiens (human) : SMPD2 (sphingomyelin phosphodiesterase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smpd2 (sphingomyelin phosphodiesterase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smpd2 (sphingomyelin phosphodiesterase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMPD2 (sphingomyelin phosphodiesterase 2)
Canis lupus familiaris (dog) : SMPD2 (sphingomyelin phosphodiesterase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smpd2 (sphingomyelin phosphodiesterase 2)
Sus scrofa (pig) : SMPD2 (sphingomyelin phosphodiesterase 2)
Chlorocebus sabaeus (African green monkey) : SMPD2 (sphingomyelin phosphodiesterase 2)
Heterocephalus glaber (naked mole-rat) : Smpd2 (sphingomyelin phosphodiesterase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1041,485,642 - 41,490,369 (-)EnsemblGRCm38mm10GRCm38
GRCm381041,487,172 - 41,490,370 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371041,206,978 - 41,210,146 (-)NCBIGRCm37mm9NCBIm37
MGSCv361041,175,587 - 41,178,755 (-)NCBImm8
Celera1042,373,425 - 42,376,593 (-)NCBICelera
Cytogenetic Map10B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Smpd2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732431
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.