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Gene: TXN (thioredoxin) Homo sapiens
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Symbol: TXN
Name: thioredoxin
Description: Exhibits RNA binding activity. Involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of DNA binding activity; and positive regulation of peptidyl-serine phosphorylation. Localizes to the cytosol and nucleoplasm. Biomarker of dilated cardiomyopathy; intermediate coronary syndrome; myocardial infarction; and myocarditis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADF; ATL-derived factor; DKFZp686B1993; MGC61975; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin delta 3; TRDX; TRX; TRX1; TXN delta 3
Orthologs:
Mus musculus (house mouse) : Txn1 (thioredoxin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Txn1 (thioredoxin 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TXN (thioredoxin)
Canis lupus familiaris (dog) : LOC100687127 (thioredoxin-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txn (thioredoxin)
Sus scrofa (pig) : TXN (thioredoxin)
more info ...
Related Pseudogenes: TXNP1   TXNP2   TXNP3   TXNP4   TXNP5   TXNP6   TXNP7  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389110,243,810 - 110,256,507 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379113,006,092 - 113,018,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369112,046,131 - 112,058,599 (-)NCBINCBI36hg18NCBI36
Build 349110,085,864 - 110,098,333NCBI
Celera983,507,936 - 83,520,398 (-)NCBI
Cytogenetic Map9q31.3NCBI
HuRef982,607,811 - 82,620,710 (-)NCBIHuRef
CHM1_19113,152,543 - 113,165,343 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TXN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732441
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.