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Gene: Ezr (ezrin) Mus musculus
Symbol: Ezr
Name: ezrin
Description: Exhibits disordered domain specific binding activity and protein C-terminus binding activity. Involved in several processes, including intestinal D-glucose absorption; positive regulation of growth; and terminal web assembly. Localizes to several cellular components, including brush border; microvillus; and uropod. Predicted to colocalize with focal adhesion. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human EZR (ezrin); PARTICIPATES IN FasL mediated signaling pathway; parathyroid hormone signaling pathway; protein kinase A (PKA) signaling pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW146364; cytovillin; MGC107499; p81; R75297; Vil2; villin 2; villin-2
Homo sapiens (human) : EZR (ezrin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ezr (ezrin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ezr (ezrin)
Pan paniscus (bonobo/pygmy chimpanzee) : EZR (ezrin)
Canis lupus familiaris (dog) : EZR (ezrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ezr (ezrin)
Sus scrofa (pig) : EZR (ezrin)
Chlorocebus sabaeus (African green monkey) : EZR (ezrin)
Heterocephalus glaber (naked mole-rat) : Ezr (ezrin)
more info ...
Related Pseudogenes: Gm17832   Gm5739  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl176,738,041 - 6,782,784 (-)EnsemblGRCm38mm10GRCm38
GRCm38176,738,131 - 6,782,780 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37176,942,480 - 6,987,129 (-)NCBIGRCm37mm9NCBIm37
MGSCv36176,587,789 - 6,632,438 (-)NCBImm8
Celera1514,687,905 - 14,732,667 (+)NCBICelera
Cytogenetic Map17A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ezr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732447
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.