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Gene: Ezr (ezrin) Mus musculus
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Symbol: Ezr
Name: ezrin
Description: Exhibits disordered domain specific binding activity and protein C-terminus binding activity. Involved in several processes, including intestinal D-glucose absorption; positive regulation of growth; and terminal web assembly. Localizes to several cellular components, including brush border; microvillus; and uropod. Predicted to colocalize with focal adhesion. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human EZR (ezrin); PARTICIPATES IN FasL mediated signaling pathway; parathyroid hormone signaling pathway; protein kinase A (PKA) signaling pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW146364; cytovillin; MGC107499; p81; R75297; Vil2; villin 2; villin-2
Orthologs:
Homo sapiens (human) : EZR (ezrin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ezr (ezrin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ezr (ezrin)
Pan paniscus (bonobo/pygmy chimpanzee) : EZR (ezrin)
Canis lupus familiaris (dog) : EZR (ezrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ezr (ezrin)
Sus scrofa (pig) : EZR (ezrin)
Chlorocebus sabaeus (African green monkey) : EZR (ezrin)
Heterocephalus glaber (naked mole-rat) : Ezr (ezrin)
more info ...
Related Pseudogenes: Gm17832   Gm5739  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl176,738,041 - 6,782,784 (-)EnsemblGRCm38mm10GRCm38
GRCm38176,738,131 - 6,782,780 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37176,942,480 - 6,987,129 (-)NCBIGRCm37mm9NCBIm37
MGSCv36176,587,789 - 6,632,438 (-)NCBImm8
Celera1514,687,905 - 14,732,667 (+)NCBICelera
Cytogenetic Map17A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ezr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732447
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.