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Gene: POU1F1 (POU class 1 homeobox 1) Homo sapiens
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Symbol: POU1F1
Name: POU class 1 homeobox 1
CRRD ID: 732450
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific double-stranded DNA binding activity; and transcription factor binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Implicated in panhypopituitarism and pituitary gland disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPHD1; GHF-1; growth hormone factor 1; Pit-1; PIT1; pituitary transcript factor 1; pituitary-specific positive transcription factor 1; pituitary-specific transcription factor 1; POU domain, class 1, transcription factor 1; POU1F1a
Orthologs:
Mus musculus (house mouse) : Pou1f1 (POU domain, class 1, transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou1f1 (POU class 1 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou1f1 (POU class 1 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU1F1 (POU class 1 homeobox 1)
Canis lupus familiaris (dog) : POU1F1 (POU class 1 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou1f1 (POU class 1 homeobox 1)
Sus scrofa (pig) : POU1F1 (POU class 1 homeobox 1)
Chlorocebus sabaeus (African green monkey) : POU1F1 (POU class 1 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pou1f1 (POU class 1 homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl387,259,404 - 87,276,584 (-)EnsemblGRCh38hg38GRCh38
GRCh38387,259,404 - 87,276,584 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37387,308,783 - 87,325,737 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36387,391,473 - 87,408,427 (-)NCBINCBI36hg18NCBI36
Build 34387,391,472 - 87,408,427NCBI
Celera388,061,261 - 88,078,194 (-)NCBI
Cytogenetic Map3p11.2NCBI
HuRef387,322,012 - 87,338,945 (-)NCBIHuRef
CHM1_1387,261,327 - 87,278,276 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on POU1F1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732450
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.