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Gene: RNF40 (ring finger protein 40) Homo sapiens
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Symbol: RNF40
Name: ring finger protein 40
Description: Exhibits mRNA 3'-UTR binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Contributes to ubiquitin-protein transferase activity. Involved in histone ubiquitination; negative regulation of mRNA polyadenylation; and positive regulation of histone H2B ubiquitination. Localizes to the HULC complex and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; BRE1B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; KIAA0661; MGC13051; Rb-associated protein; RBP95; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; STARING
Orthologs:
Mus musculus (house mouse) : Rnf40 (ring finger protein 40)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf40 (ring finger protein 40)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf40 (ring finger protein 40)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF40 (ring finger protein 40)
Canis lupus familiaris (dog) : RNF40 (ring finger protein 40)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf40 (ring finger protein 40)
Sus scrofa (pig) : RNF40 (ring finger protein 40)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,761,612 - 30,800,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371630,772,933 - 30,787,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,681,131 - 30,694,040 (+)NCBINCBI36hg18NCBI36
Build 341630,681,130 - 30,694,037NCBI
Celera1629,510,882 - 29,523,813 (-)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1628,335,742 - 28,350,458 (+)NCBIHuRef
CHM1_11632,090,075 - 32,104,789 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RNF40
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732458
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.