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Gene: RASA1 (RAS p21 protein activator 1) Homo sapiens
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Symbol: RASA1
Name: RAS p21 protein activator 1
Description: Exhibits several functions, including GTPase activator activity; GTPase binding activity; and phosphotyrosine residue binding activity. Involved in several processes, including blood vessel morphogenesis; negative regulation of cell-matrix adhesion; and regulation of actin filament polymerization. Predicted to localize to the cytosol. Implicated in arteriovenous malformation and basal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CM-AVM; CMAVM; CMAVM1; DKFZp434N071; GAP; GTPase-activating protein; p120; p120GAP; p120RASGAP; PKWS; ras GTPase-activating protein 1; RAS p21 protein activator (GTPase activating protein) 1; RASA; RASGAP; triphosphatase-activating protein
Orthologs:
Mus musculus (house mouse) : Rasa1 (RAS p21 protein activator 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rasa1 (RAS p21 protein activator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasa1 (RAS p21 protein activator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASA1 (RAS p21 protein activator 1)
Canis lupus familiaris (dog) : RASA1 (RAS p21 protein activator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasa1 (RAS p21 protein activator 1)
Sus scrofa (pig) : RASA1 (RAS p21 protein activator 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38587,267,845 - 87,391,926 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37586,564,070 - 86,687,743 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36586,599,907 - 86,723,489 (+)NCBINCBI36hg18NCBI36
Build 34586,600,521 - 86,723,488NCBI
Celera582,456,373 - 82,579,983 (+)NCBI
Cytogenetic Map5q14.3NCBI
HuRef581,768,403 - 81,891,908 (+)NCBIHuRef
CHM1_1585,997,132 - 86,120,771 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RASA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732468
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.