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Gene: Rasa1 (RAS p21 protein activator 1) Mus musculus
Symbol: Rasa1
Name: RAS p21 protein activator 1
Description: Predicted to have several functions, including GTPase activator activity; enzyme binding activity; and ion channel binding activity. Predicted to be involved in several processes, including activation of GTPase activity; cellular response to growth factor stimulus; and positive regulation of glucose import. Localizes to the plasma membrane and ruffle. Human ortholog(s) of this gene implicated in arteriovenous malformation and basal cell carcinoma. Is expressed in brain and embryo. Orthologous to human RASA1 (RAS p21 protein activator 1); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; insulin signaling pathway; INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gap; GTPase-activating protein; MGC7759; p120-rasGAP; ras GTPase-activating protein 1; Rasa; RasGAP
Homo sapiens (human) : RASA1 (RAS p21 protein activator 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rasa1 (RAS p21 protein activator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasa1 (RAS p21 protein activator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASA1 (RAS p21 protein activator 1)
Canis lupus familiaris (dog) : RASA1 (RAS p21 protein activator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasa1 (RAS p21 protein activator 1)
Sus scrofa (pig) : RASA1 (RAS p21 protein activator 1)
Chlorocebus sabaeus (green monkey) : RASA1 (RAS p21 protein activator 1)
Heterocephalus glaber (naked mole-rat) : Rasa1 (RAS p21 protein activator 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1385,214,780 - 85,289,130 (-)Ensembl
GRCm381385,214,699 - 85,289,486 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371385,354,304 - 85,429,091 (-)NCBIGRCm37mm9NCBIm37
MGSCv361385,689,136 - 85,729,574 (-)NCBImm8
Celera1387,446,946 - 87,523,497 (-)NCBICelera
Cytogenetic Map13 C3NCBI
cM Map1345.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rasa1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732469
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.