Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HCK (HCK proto-oncogene, Src family tyrosine kinase) Homo sapiens
Analyze
Symbol: HCK
Name: HCK proto-oncogene, Src family tyrosine kinase
Description: Exhibits phosphotyrosine residue binding activity and protein tyrosine kinase activity. Involved in several processes, including protein phosphorylation; regulation of DNA-binding transcription factor activity; and regulation of organelle organization. Localizes to several cellular components, including the caveola; extrinsic component of cytoplasmic side of plasma membrane; and focal adhesion. Colocalizes with the actin filament.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hematopoietic cell kinase; hemopoietic cell kinase; JTK9; p59-HCK/p60-HCK; p59Hck; p61Hck; tyrosine-protein kinase HCK
Orthologs:
Mus musculus (house mouse) : Hck (hemopoietic cell kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hck (HCK proto-oncogene, Src family tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hck (HCK proto-oncogene, Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
Canis lupus familiaris (dog) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hck (HCK proto-oncogene, Src family tyrosine kinase)
Sus scrofa (pig) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,052,242 - 32,101,843 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372030,639,991 - 30,689,659 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,103,718 - 30,153,320 (+)NCBINCBI36hg18NCBI36
Build 342030,103,717 - 30,153,316NCBI
Celera2027,396,349 - 27,446,028 (+)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2027,428,653 - 27,478,333 (+)NCBIHuRef
CHM1_12030,543,895 - 30,593,543 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HCK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732471
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.