Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tgm2 (transglutaminase 2, C polypeptide) Mus musculus
Analyze
Symbol: Tgm2
Name: transglutaminase 2, C polypeptide
Description: Exhibits protein-glutamine gamma-glutamyltransferase activity. Involved in cellular calcium ion homeostasis; positive regulation of cell adhesion; and salivary gland morphogenesis. Localizes to the collagen-containing extracellular matrix. Used to study maturity-onset diabetes of the young. Is expressed in several structures, including central nervous system; cranium; genitourinary system; mesothelium; and sensory organ. Orthologous to human TGM2 (transglutaminase 2); PARTICIPATES IN eicosanoid signaling pathway; Huntington's disease pathway; INTERACTS WITH 1,1-dichloroethene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C polypeptide; G[a]h; protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; TG C; TG(C); TG2; TGase C; TGase-2; TGase2; TGC; tissue transglutaminase; transglutaminase C; transglutaminase-2; tTG; tTGas
Orthologs:
Homo sapiens (human) : TGM2 (transglutaminase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgm2 (transglutaminase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgm2 (transglutaminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TGM2 (transglutaminase 2)
Canis lupus familiaris (dog) : TGM2 (transglutaminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgm2 (transglutaminase 2)
Sus scrofa (pig) : TGM2 (transglutaminase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382158,116,405 - 158,146,392 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372157,942,141 - 157,972,128 (-)NCBIGRCm37mm9NCBIm37
MGSCv362157,807,846 - 157,837,833 (-)NCBImm8
Celera2164,061,515 - 164,091,498 (-)NCBICelera
Cytogenetic Map2 H1NCBI
cM Map278.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tgm2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732488
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.