Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta) Homo sapiens
Analyze
Symbol: PIK3CB
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Description: Exhibits kinase activity. Involved in several processes, including phosphatidylinositol 3-kinase signaling; positive regulation of neutrophil apoptotic process; and regulation of cell-matrix adhesion. Localizes to the midbody; nucleolus; and nucleoplasm. Implicated in glioblastoma multiforme; prostate adenocarcinoma; and prostate cancer. Biomarker of endometrial cancer; glioblastoma multiforme; prostate cancer; rectal neoplasm; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp779K1237; MGC133043; P110BETA; phosphatidylinositol 3-kinase, catalytic subunit, beta isoform; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; phosphoinositide-3-kinase, catalytic, beta polypeptide; PI3-kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K-beta; PI3KBETA; PIK3C1; PtdIns-3-kinase p110; ptdIns-3-kinase subunit beta; ptdIns-3-kinase subunit p110-beta
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383138,652,698 - 138,834,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373138,371,540 - 138,553,780 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363139,856,921 - 139,960,875 (-)NCBINCBI36hg18NCBI36
Build 343139,856,928 - 139,960,883NCBI
Celera3136,799,538 - 136,904,134 (-)NCBI
Cytogenetic Map3q22.3NCBI
HuRef3135,746,166 - 135,853,444 (-)NCBIHuRef
CHM1_13138,335,402 - 138,442,207 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIK3CB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732496
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.