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Gene: TRA2B (transformer 2 beta homolog) Homo sapiens
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Symbol: TRA2B
Name: transformer 2 beta homolog
Description: Exhibits RNA binding activity; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including cellular response to glucose stimulus; mRNA splicing, via spliceosome; and regulation of mRNA splicing, via spliceosome. Localizes to the nucleoplasm and spliceosomal complex. Biomarker of macular degeneration.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686F18120; Htra2-beta; PPP1R156; SFRS10; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila); SRFS10; TRA-2 beta; TRA2-BETA; TRAN2B; transformer 2 beta homolog (Drosophila); transformer 2 homolog; transformer-2 protein homolog B; transformer-2 protein homolog beta; transformer-2-beta
Orthologs:
Mus musculus (house mouse) : Tra2b (transformer 2 beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tra2b (transformer 2 beta homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tra2b (transformer 2 beta homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : TRA2B (transformer 2 beta homolog)
Canis lupus familiaris (dog) : TRA2B (transformer 2 beta homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tra2b (transformer 2 beta homolog)
Sus scrofa (pig) : TRA2B (transformer 2 beta homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,914,558 - 185,938,027 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373185,632,356 - 185,655,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,117,226 - 187,138,450 (-)NCBINCBI36hg18NCBI36
Build 343187,117,238 - 187,138,458NCBI
Celera3184,070,271 - 184,093,839 (-)NCBI
Cytogenetic Map3q27.2NCBI
HuRef3183,042,973 - 183,066,541 (-)NCBIHuRef
CHM1_13185,595,300 - 185,618,882 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TRA2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732515
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.