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Gene: Dlk1 (delta like non-canonical Notch ligand 1) Mus musculus
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Symbol: Dlk1
Name: delta like non-canonical Notch ligand 1
Description: Predicted to have calcium ion binding activity. Involved in several processes, including growth; negative regulation of vascular endothelial cell proliferation; and positive regulation of bone resorption. Localizes to the external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and skeletal system. Orthologous to human DLK1 (delta like non-canonical Notch ligand 1); PARTICIPATES IN forkhead class A signaling pathway; Notch signaling pathway; p38 MAPK signaling pathway; INTERACTS WITH 1,4-bis(2-ethylhexyl) sulfosuccinate; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose 6-phosphate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adipocyte differentiation inhibitor protein; AW742678; delta-like 1 homolog; delta-like 1 homolog (Drosophila); DLK-1; DlkI; FA1; fetal antigen 1; Ly107; Peg9; pG2; preadipocyte factor 1; pref-1; protein delta homolog 1; SCP1; stromal cell derived protein 1; ZOG
Orthologs:
Homo sapiens (human) : DLK1 (delta like non-canonical Notch ligand 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dlk1 (delta like non-canonical Notch ligand 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlk1 (delta like non-canonical Notch ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DLK1 (delta like non-canonical Notch ligand 1)
Canis lupus familiaris (dog) : DLK1 (delta like non-canonical Notch ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlk1 (delta like non-canonical Notch ligand 1)
Sus scrofa (pig) : DLK1 (delta like non-canonical Notch ligand 1)
Chlorocebus sabaeus (African green monkey) : DLK1 (delta like non-canonical Notch ligand 1)
Heterocephalus glaber (naked mole-rat) : Dlk1 (delta like non-canonical Notch ligand 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12109,452,823 - 109,463,336 (+)Ensembl
GRCm3812109,452,485 - 109,463,336 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712110,691,033 - 110,701,546 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612109,901,030 - 109,908,498 (+)NCBImm8
Celera12110,648,411 - 110,658,915 (+)NCBICelera
Cytogenetic Map12 F1NCBI
cM Map1260.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Dlk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732543
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.