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Gene: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3) Mus musculus
Symbol: Hsd17b3
Name: hydroxysteroid (17-beta) dehydrogenase 3
CRRD ID: 732551
Description: Predicted to have estradiol 17-beta-dehydrogenase activity; testosterone 17-beta-dehydrogenase (NADP+) activity; and testosterone dehydrogenase (NAD+) activity. Predicted to be involved in steroid biosynthetic process. Predicted to localize to endoplasmic reticulum. Is expressed in testis. Human ortholog(s) of this gene implicated in disorders of sexual development. Orthologous to human HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 17(beta)HSD type 3; 17-beta-HSD 3; 17-beta-hydroxysteroid dehydrogenase type 3; testicular 17-beta-hydroxysteroid dehydrogenase; testosterone 17-beta-dehydrogenase 3
Homo sapiens (human) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Canis lupus familiaris (dog) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3)
Sus scrofa (pig) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Chlorocebus sabaeus (African green monkey) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Heterocephalus glaber (naked mole-rat) : Hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1364,058,266 - 64,089,230 (-)EnsemblGRCm38mm10GRCm38
GRCm381364,058,274 - 64,089,262 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371364,159,582 - 64,190,509 (-)NCBIGRCm37mm9NCBIm37
MGSCv361364,067,496 - 64,098,408 (-)NCBImm8
Celera1365,722,306 - 65,753,080 (-)NCBICelera
Cytogenetic Map13B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsd17b3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732551
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.