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Gene: CACNB2 (calcium voltage-gated channel auxiliary subunit beta 2) Homo sapiens
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Symbol: CACNB2
Name: calcium voltage-gated channel auxiliary subunit beta 2
Description: Exhibits voltage-gated calcium channel activity. Contributes to high voltage-gated calcium channel activity and voltage-gated calcium channel activity involved in AV node cell action potential. Involved in calcium ion import; cardiac conduction; and positive regulation of calcium ion transport. Localizes to the L-type voltage-gated calcium channel complex. Implicated in Brugada syndrome 4; hypertension; and hypertrophic cardiomyopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAB2; CACNLB2; calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CAVB2; FLJ23743; lambert-Eaton myasthenic syndrome antigen B; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; voltage-dependent L-type calcium channel subunit beta-2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1018,140,677 - 18,543,557 (+)EnsemblGRCh38hg38GRCh38
GRCh381018,140,424 - 18,545,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371018,429,373 - 18,830,688 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361018,469,612 - 18,870,694 (+)NCBINCBI36hg18NCBI36
Build 341018,729,966 - 18,870,044NCBI
Celera1018,116,041 - 18,517,577 (+)NCBI
Cytogenetic Map10p12.33-p12.31NCBI
HuRef1018,094,960 - 18,495,622 (+)NCBIHuRef
CHM1_11018,429,651 - 18,830,663 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CACNB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732576
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.