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Gene: TSHB (thyroid stimulating hormone subunit beta) Homo sapiens
Symbol: TSHB
Name: thyroid stimulating hormone subunit beta
Description: Predicted to contribute to hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway and hormone-mediated signaling pathway. Predicted to localize to the cytoplasm and extracellular space. Implicated in congenital nongoitrous hypothyroidism 4 and hypothyroidism. Biomarker of hyperglycemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHNG4; thyroid stimulating hormone beta; thyroid stimulating hormone, beta; thyroid-stimulating hormone subunit beta; thyrotropin beta chain; thyrotropin beta subunit; thyrotropin subunit beta; TSH-B; TSH-BETA
Mus musculus (house mouse) : Tshb (thyroid stimulating hormone, beta subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tshb (thyroid stimulating hormone subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tshb (thyroid stimulating hormone subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : TSHB (thyroid stimulating hormone subunit beta)
Canis lupus familiaris (dog) : TSHB (thyroid stimulating hormone subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tshb (thyroid stimulating hormone subunit beta)
Sus scrofa (pig) : TSHB (thyroid stimulating hormone subunit beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1115,029,824 - 115,034,309 (+)Ensembl
GRCh381115,029,826 - 115,035,935 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371115,572,445 - 115,576,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361115,373,938 - 115,378,464 (+)NCBINCBI36hg18NCBI36
Build 341115,284,456 - 115,288,983NCBI
Celera1113,801,633 - 113,806,160 (+)NCBI
Cytogenetic Map1p13.2NCBI
HuRef1113,430,739 - 113,435,225 (+)NCBIHuRef
CHM1_11115,687,686 - 115,692,176 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TSHB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732605
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.