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Gene: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) Homo sapiens
Symbol: CHRNA3
Name: cholinergic receptor nicotinic alpha 3 subunit
Description: Exhibits acetylcholine receptor activity and acetylcholine-gated cation-selective channel activity. Involved in several processes, including behavioral response to nicotine; signal transduction; and synaptic transmission involved in micturition. Localizes to acetylcholine-gated channel complex. Implicated in lung cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acetylcholine receptor, nicotinic, alpha 3 (neuronal); BAIPRCK; cholinergic receptor, nicotinic alpha 3; cholinergic receptor, nicotinic, alpha 3 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 3; LNCR2; MGC104879; NACHRA3; neuronal acetylcholine receptor subunit alpha-3; neuronal nicotinic acetylcholine receptor, alpha3 subunit; PAOD2
Mus musculus (house mouse) : Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chrna3 (cholinergic receptor nicotinic alpha 3 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrna3 (cholinergic receptor nicotinic alpha 3 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit)
Canis lupus familiaris (dog) : CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna3 (cholinergic receptor nicotinic alpha 3 subunit)
Sus scrofa (pig) : CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit)
Heterocephalus glaber (naked mole-rat) : Chrna3 (cholinergic receptor nicotinic alpha 3 subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1578,593,052 - 78,621,295 (-)EnsemblGRCh38hg38GRCh38
GRCh381578,593,052 - 78,620,996 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371578,885,394 - 78,913,637 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,674,706 - 76,700,377 (-)NCBINCBI36hg18NCBI36
Build 341576,674,706 - 76,700,377NCBI
Celera1555,821,707 - 55,849,902 (-)NCBI
Cytogenetic Map15q25.1NCBI
HuRef1555,642,483 - 55,671,504 (-)NCBIHuRef
CHM1_11579,003,962 - 79,032,196 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHRNA3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732613
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.