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Gene: IGF2R (insulin like growth factor 2 receptor) Homo sapiens
Symbol: IGF2R
Name: insulin like growth factor 2 receptor
CRRD ID: 732660
Description: Exhibits identical protein binding activity; phosphoprotein binding activity; and retromer complex binding activity. Involved in positive regulation by host of viral process. Localizes to cell surface; cytoplasmic vesicle; and trans-Golgi network. Implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Biomarker of breast carcinoma; colon carcinoma; hepatocellular carcinoma; multiple myeloma; and non-Hodgkin lymphoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 300 kDa mannose 6-phosphate receptor; cation-independent mannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptor; CD222; CI Man-6-P receptor; CI-M6PR; CI-MPR; CIMPR; IGF-II receptor; insulin-like growth factor 2 receptor; insulin-like growth factor II receptor; M6P-R; M6P/IGF2 receptor; M6P/IGF2R; M6PR; mannose 6-phosphate/insulin-like growth factor-II receptor; MPR 300; MPR1; MPR300; MPRI
Mus musculus (house mouse) : Igf2r (insulin-like growth factor 2 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igf2r (insulin-like growth factor 2 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2r (insulin like growth factor 2 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2R (insulin like growth factor 2 receptor)
Canis lupus familiaris (dog) : IGF2R (insulin like growth factor 2 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2r (insulin like growth factor 2 receptor)
Sus scrofa (pig) : IGF2R (insulin like growth factor 2 receptor)
Chlorocebus sabaeus (African green monkey) : IGF2R (insulin like growth factor 2 receptor)
Heterocephalus glaber (naked mole-rat) : Igf2r (insulin like growth factor 2 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl6159,969,099 - 160,113,507 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl6159,969,082 - 160,113,507 (+)EnsemblGRCh38hg38GRCh38
GRCh386159,969,082 - 160,111,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376160,390,131 - 160,527,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,310,121 - 160,447,573 (+)NCBINCBI36hg18NCBI36
Build 346160,360,541 - 160,497,992NCBI
Celera6161,035,974 - 161,173,355 (+)NCBI
Cytogenetic Map6q25.3NCBI
HuRef6157,860,740 - 157,998,270 (+)NCBIHuRef
CHM1_16160,652,348 - 160,794,781 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGF2R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732660
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.