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Gene: IGF2R (insulin like growth factor 2 receptor) Homo sapiens
Symbol: IGF2R
Name: insulin like growth factor 2 receptor
Description: Exhibits identical protein binding activity and phosphoprotein binding activity. Involved in positive regulation by host of viral process. Localizes to the cell surface; cytoplasmic vesicle; and trans-Golgi network. Implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Biomarker of breast carcinoma; colon carcinoma; hepatocellular carcinoma; multiple myeloma; and non-Hodgkin lymphoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 300 kDa mannose 6-phosphate receptor; cation-independent mannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptor; CD222; CI Man-6-P receptor; CI-M6PR; CI-MPR; CIMPR; IGF-II receptor; insulin-like growth factor 2 receptor; insulin-like growth factor II receptor; M6P-R; M6P/IGF2 receptor; M6P/IGF2R; M6PR; mannose 6-phosphate/insulin-like growth factor-II receptor; MPR 300; MPR1; MPR300; MPRI
Mus musculus (house mouse) : Igf2r (insulin-like growth factor 2 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igf2r (insulin-like growth factor 2 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2r (insulin like growth factor 2 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2R (insulin like growth factor 2 receptor)
Canis lupus familiaris (dog) : IGF2R (insulin like growth factor 2 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2r (insulin like growth factor 2 receptor)
Sus scrofa (pig) : IGF2R (insulin like growth factor 2 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh386159,969,099 - 160,111,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376160,390,131 - 160,527,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,310,121 - 160,447,573 (+)NCBINCBI36hg18NCBI36
Build 346160,360,541 - 160,497,992NCBI
Celera6161,035,974 - 161,173,355 (+)NCBI
Cytogenetic Map6q25.3NCBI
HuRef6157,860,740 - 157,998,270 (+)NCBIHuRef
CHM1_16160,652,348 - 160,794,781 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGF2R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732660
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-22
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.