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Gene: Igf2r (insulin-like growth factor 2 receptor) Mus musculus
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Symbol: Igf2r
Name: insulin-like growth factor 2 receptor
CRRD ID: 732661
Description: Exhibits insulin-like growth factor binding activity and mannose binding activity. Predicted to be involved in several processes, including liver development; positive regulation by host of viral process; and response to retinoic acid. Localizes to membrane and nuclear envelope lumen. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Orthologous to human IGF2R (insulin like growth factor 2 receptor); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-; CI-MPR; IGF-II receptor; IGF-II/CI-MPR; insulin-like growth factor II receptor; M6P/IG; M6P/IGF2 receptor; M6P/IGF2R; M6PR; mannose-6-phosphate receptor, cation independent; MPR 300; Mpr3; Mpr300
Orthologs:
Homo sapiens (human) : IGF2R (insulin like growth factor 2 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igf2r (insulin-like growth factor 2 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2r (insulin like growth factor 2 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2R (insulin like growth factor 2 receptor)
Canis lupus familiaris (dog) : IGF2R (insulin like growth factor 2 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2r (insulin like growth factor 2 receptor)
Sus scrofa (pig) : IGF2R (insulin like growth factor 2 receptor)
Chlorocebus sabaeus (African green monkey) : IGF2R (insulin like growth factor 2 receptor)
Heterocephalus glaber (naked mole-rat) : Igf2r (insulin like growth factor 2 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,901,293 - 12,988,593 (-)NCBI
GRCm381712,682,406 - 12,769,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,875,272 - 12,962,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv361712,525,771 - 12,613,022 (-)NCBImm8
Celera1712,714,412 - 12,801,753 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Igf2r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732661
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.