Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Igf2r (insulin-like growth factor 2 receptor) Mus musculus
Symbol: Igf2r
Name: insulin-like growth factor 2 receptor
CRRD ID: 732661
Description: Exhibits insulin-like growth factor binding activity and mannose binding activity. Predicted to be involved in several processes, including liver development; positive regulation by host of viral process; and response to retinoic acid. Localizes to membrane and nuclear envelope lumen. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Orthologous to human IGF2R (insulin like growth factor 2 receptor); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-; CI-MPR; IGF-II receptor; IGF-II/CI-MPR; insulin-like growth factor II receptor; M6P/IG; M6P/IGF2 receptor; M6P/IGF2R; M6PR; mannose-6-phosphate receptor, cation independent; MPR 300; Mpr3; Mpr300
Homo sapiens (human) : IGF2R (insulin like growth factor 2 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igf2r (insulin-like growth factor 2 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2r (insulin like growth factor 2 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2R (insulin like growth factor 2 receptor)
Canis lupus familiaris (dog) : IGF2R (insulin like growth factor 2 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2r (insulin like growth factor 2 receptor)
Sus scrofa (pig) : IGF2R (insulin like growth factor 2 receptor)
Chlorocebus sabaeus (African green monkey) : IGF2R (insulin like growth factor 2 receptor)
Heterocephalus glaber (naked mole-rat) : Igf2r (insulin like growth factor 2 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391712,901,293 - 12,988,593 (-)NCBI
GRCm381712,682,406 - 12,769,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,875,272 - 12,962,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv361712,525,771 - 12,613,022 (-)NCBImm8
Celera1712,714,412 - 12,801,753 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Igf2r
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732661
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.