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Gene: Fen1 (flap structure specific endonuclease 1) Mus musculus
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Symbol: Fen1
Name: flap structure specific endonuclease 1
Description: ENCODES a protein that exhibits DNA binding; exonuclease activity; flap endonuclease activity; INVOLVED IN DNA repair; DNA replication; DNA replication, removal of RNA primer (ortholog); PARTICIPATES IN base excision repair pathway; DNA replication pathway; non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH abnormal blastocyst morphology; abnormal cell physiology; abnormal DNA repair; ASSOCIATED WITH adenocarcinoma; Autoimmune Diseases; Intestinal Neoplasms; FOUND IN mitochondrion (ortholog); nuclear chromosome, telomeric region (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW538437; FEN-1; flap endonuclease 1; flap structure-specific endonuclease 1
Orthologs:
Homo sapiens (human) : FEN1 (flap structure-specific endonuclease 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fen1 (flap structure-specific endonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fen1 (flap structure-specific endonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FEN1 (flap structure-specific endonuclease 1)
Canis lupus familiaris (dog) : FEN1 (flap structure-specific endonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fen1 (flap structure-specific endonuclease 1)
Sus scrofa (pig) : FEN1 (flap structure-specific endonuclease 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381910,199,132 - 10,204,393 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371910,273,629 - 10,278,433 (-)NCBIGRCm37mm9NCBIm37
MGSCv361910,266,184 - 10,270,988 (-)NCBImm8
Celera1910,895,049 - 10,899,860 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fen1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732680
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.