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Gene: AKR7A2 (aldo-keto reductase family 7 member A2) Homo sapiens
Symbol: AKR7A2
Name: aldo-keto reductase family 7 member A2
Description: Exhibits phenanthrene-9,10-epoxide hydrolase activity. Involved in daunorubicin metabolic process and doxorubicin metabolic process. Localizes to the cytosol. Biomarker of Alzheimer's disease and pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1-AR 1; AFB1-AR1; aflatoxin aldehyde reductase; aflatoxin B1 aldehyde reductase member 2; aflatoxin beta1 aldehyde reductase; AKR7; aldo-keto reductase family 7, member A2; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase); aldoketoreductase 7; epididymis secretory sperm binding protein Li 166mP; HEL-S-166mP; SSA reductase; succinic semialdehyde reductase
Mus musculus (house mouse) : Akr7a5 (aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Akr7a2 (aldo-keto reductase family 7, member A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akr7a2 (aldo-keto reductase family 7 member A2)
Canis lupus familiaris (dog) : AKR7A2 (aldo-keto reductase family 7 member A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr7a2 (aldo-keto reductase family 7 member A2)
Sus scrofa (pig) : AKR7A2 (aldo-keto reductase family 7 member A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38119,302,708 - 19,312,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37119,629,202 - 19,638,640 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,503,046 - 19,511,227 (-)NCBINCBI36hg18NCBI36
Build 34119,375,768 - 19,383,946NCBI
Celera117,957,442 - 17,965,624 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef117,875,577 - 17,884,829 (-)NCBIHuRef
CHM1_1119,738,505 - 19,747,943 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AKR7A2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732683
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.