Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: AKR7A2 (aldo-keto reductase family 7 member A2) Homo sapiens
Analyze
Symbol: AKR7A2
Name: aldo-keto reductase family 7 member A2
Description: Exhibits phenanthrene-9,10-epoxide hydrolase activity. Involved in daunorubicin metabolic process and doxorubicin metabolic process. Localizes to the cytosol. Biomarker of Alzheimer's disease and pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1-AR 1; AFB1-AR1; aflatoxin aldehyde reductase; aflatoxin B1 aldehyde reductase member 2; aflatoxin beta1 aldehyde reductase; AKR7; aldo-keto reductase family 7, member A2; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase); aldoketoreductase 7; epididymis secretory sperm binding protein Li 166mP; HEL-S-166mP; SSA reductase; succinic semialdehyde reductase
Orthologs:
Mus musculus (house mouse) : Akr7a5 (aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Akr7a2 (aldo-keto reductase family 7, member A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akr7a2 (aldo-keto reductase family 7 member A2)
Canis lupus familiaris (dog) : AKR7A2 (aldo-keto reductase family 7 member A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr7a2 (aldo-keto reductase family 7 member A2)
Sus scrofa (pig) : AKR7A2 (aldo-keto reductase family 7 member A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,302,708 - 19,312,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37119,629,202 - 19,638,640 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,503,046 - 19,511,227 (-)NCBINCBI36hg18NCBI36
Build 34119,375,768 - 19,383,946NCBI
Celera117,957,442 - 17,965,624 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef117,875,577 - 17,884,829 (-)NCBIHuRef
CHM1_1119,738,505 - 19,747,943 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AKR7A2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732683
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.