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Gene: KCNN4 (potassium calcium-activated channel subfamily N member 4) Homo sapiens
Symbol: KCNN4
Name: potassium calcium-activated channel subfamily N member 4
Description: Exhibits calcium-activated potassium channel activity and protein phosphatase binding activity. Involved in calcium ion transport; positive regulation of T cell receptor signaling pathway; and stabilization of membrane potential. Localizes to the plasma membrane and vesicle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; intermediate conductance calcium-activated potassium channel protein 4; KCa3.1; KCA4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; putative Gardos channel; SK4; SKCa 4; SKCa4; small conductance calcium-activated potassium channel 4
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1943,766,533 - 43,781,257 (-)EnsemblGRCh38hg38GRCh38
GRCh381943,766,533 - 43,782,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371944,270,685 - 44,286,269 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,962,525 - 48,977,249 (-)NCBINCBI36hg18NCBI36
Build 341948,962,524 - 48,977,249NCBI
Celera1941,074,253 - 41,088,976 (-)NCBI
Cytogenetic Map19q13.31NCBI
HuRef1940,702,891 - 40,717,615 (-)NCBIHuRef
CHM1_11944,272,786 - 44,287,492 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNN4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732698
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.