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Gene: DBN1 (drebrin 1) Homo sapiens
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Symbol: DBN1
Name: drebrin 1
CRRD ID: 732725
Description: Exhibits cadherin binding activity. Involved in cytoplasmic sequestering of protein. Localizes to cytoplasm; cytoskeleton; and dendrite. Predicted to colocalize with actin filament and cell-cell junction. Biomarker of Alzheimer's disease; Down syndrome; and cognitive disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D0S117E; developmentally-regulated brain protein; DKFZp434D064; drebrin; drebrin A; drebrin E; drebrin E2; drebrin-1
Orthologs:
Mus musculus (house mouse) : Dbn1 (drebrin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dbn1 (drebrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dbn1 (drebrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DBN1 (drebrin 1)
Canis lupus familiaris (dog) : DBN1 (drebrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dbn1 (drebrin 1)
Sus scrofa (pig) : DBN1 (drebrin 1)
Chlorocebus sabaeus (African green monkey) : DBN1 (drebrin 1)
Heterocephalus glaber (naked mole-rat) : Dbn1 (drebrin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5177,456,608 - 177,474,401 (-)EnsemblGRCh38hg38GRCh38
GRCh385177,456,610 - 177,480,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375176,883,613 - 176,900,694 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,816,220 - 176,833,271 (-)NCBINCBI36hg18NCBI36
Build 345176,816,219 - 176,832,805NCBI
Celera5171,601,010 - 171,618,030 (+)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5171,803,862 - 171,820,946 (-)NCBIHuRef
CHM1_15176,316,642 - 176,333,751 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on DBN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732725
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.