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Gene: ADCYAP1 (adenylate cyclase activating polypeptide 1) Homo sapiens
Symbol: ADCYAP1
Name: adenylate cyclase activating polypeptide 1
Description: This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylate cyclase activating polypeptide 1 (pituitary); MGC126852; PACAP; pituitary adenylate cyclase activating polypeptide; pituitary adenylate cyclase-activating polypeptide; prepro-PACAP
Mus musculus (house mouse) : Adcyap1 (adenylate cyclase activating polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adcyap1 (adenylate cyclase activating polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcyap1 (adenylate cyclase activating polypeptide 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCYAP1 (adenylate cyclase activating polypeptide 1)
Canis lupus familiaris (dog) : ADCYAP1 (adenylate cyclase activating polypeptide 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcyap1 (adenylate cyclase activating polypeptide 1)
Sus scrofa (pig) : ADCYAP1 (adenylate cyclase activating polypeptide 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3818904,384 - 912,172 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3718904,366 - 912,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3618894,944 - 902,173 (+)NCBINCBI36hg18NCBI36
Build 3418895,386 - 901,050NCBI
Celera18779,552 - 786,777 (+)NCBI
Cytogenetic Map18p11.32NCBI
HuRef18865,131 - 872,354 (+)NCBIHuRef
CHM1_118904,574 - 911,803 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADCYAP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732730
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.