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Gene: NCOA2 (nuclear receptor coactivator 2) Homo sapiens
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Symbol: NCOA2
Name: nuclear receptor coactivator 2
Description: Exhibits RNA polymerase II-specific DNA-binding transcription factor binding activity; nuclear receptor transcription coactivator activity; and protein domain specific binding activity. Predicted to be involved in cellular response to hormone stimulus; circadian regulation of gene expression; and positive regulation of transcription by RNA polymerase II. Localizes to the nuclear body and protein-containing complex. Implicated in acute myeloid leukemia. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHe75; class E basic helix-loop-helix protein 75; glucocorticoid receptor-interacting protein-1; GRIP1; hTIF2; KAT13C; MGC138808; NCoA-2; p160 steroid receptor coactivator 2; SRC2; TIF2; transcriptional intermediary factor 2
Orthologs:
Mus musculus (house mouse) : Ncoa2 (nuclear receptor coactivator 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ncoa2 (nuclear receptor coactivator 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa2 (nuclear receptor coactivator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA2 (nuclear receptor coactivator 2)
Canis lupus familiaris (dog) : NCOA2 (nuclear receptor coactivator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa2 (nuclear receptor coactivator 2)
Sus scrofa (pig) : NCOA2 (nuclear receptor coactivator 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: GRIP1 (Gene ID: 23426) and NCOA2 (Gene ID: 10499) share the GRIP1 symbol/alias in common. GRIP1 is a widely used alternative name for nuclear receptor coactivator 2 (NCOA2), which can be confused with the official symbol for glutamate receptor-interacting protein 1 (GRIP1). [06 Jul 2018]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38870,109,770 - 70,405,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37871,021,997 - 71,316,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,186,821 - 71,478,574 (-)NCBINCBI36hg18NCBI36
Build 34871,186,820 - 71,478,574NCBI
Celera867,021,935 - 67,313,703 (-)NCBI
Cytogenetic Map8q13.3NCBI
HuRef866,517,566 - 66,809,329 (-)NCBIHuRef
CHM1_1871,077,538 - 71,372,108 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NCOA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732737
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.