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Gene: PSMC5 (proteasome 26S subunit, ATPase 5) Homo sapiens
Symbol: PSMC5
Name: proteasome 26S subunit, ATPase 5
Description: Exhibits thyrotropin-releasing hormone receptor binding activity and transcription factor binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of transcription by RNA polymerase II. Localizes to the cytoplasmic vesicle; nucleus; and proteasome complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 26S protease regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; 26S proteasome regulatory subunit 8; for proteasomal atpase (sug1); MSUG1 protein; p45; p45/SUG; proteasome (prosome, macropain) 26S subunit, ATPase, 5; proteasome 26S ATPase subunit 5; proteasome 26S subunit ATPase 5; proteasome subunit p45; S8; SUG-1; SUG1; Tat-binding protein homolog 10; TBP10; testicular tissue protein Li 149; thyroid hormone receptor-interacting protein 1; thyroid receptor interactor 1; TRIP1
Mus musculus (house mouse) : Psmc5 (protease (prosome, macropain) 26S subunit, ATPase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Psmc5 (proteasome 26S subunit, ATPase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psmc5 (proteasome 26S subunit, ATPase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PSMC5 (proteasome 26S subunit, ATPase 5)
Canis lupus familiaris (dog) : PSMC5 (proteasome 26S subunit, ATPase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psmc5 (proteasome 26S subunit, ATPase 5)
Sus scrofa (pig) : PSMC5 (proteasome 26S subunit, ATPase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381763,827,431 - 63,832,027 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371761,904,770 - 61,909,387 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,258,542 - 59,263,119 (+)NCBINCBI36hg18NCBI36
Build 341759,258,541 - 59,263,118NCBI
Celera1756,292,931 - 56,297,508 (+)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,272,832 - 57,277,449 (+)NCBIHuRef
CHM1_11761,969,121 - 61,973,738 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PSMC5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732741
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.