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Gene: NR4A1 (nuclear receptor subfamily 4 group A member 1) Homo sapiens
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Symbol: NR4A1
Name: nuclear receptor subfamily 4 group A member 1
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including cellular response to growth factor stimulus; endothelial cell migration; and positive regulation of endothelial cell proliferation. Localizes to the cytosol; nuclear membrane; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: early response protein NAK1; GFRP1; growth factor-inducible nuclear protein N10; HMR; hormone receptor; immediate early gene transcription factor ngfi-b; MGC9485; N10; NAK-1; nerve growth factor IB nuclear receptor variant 1; NGFIB; NP10; nuclear hormone receptor NUR/77; nuclear receptor subfamily 4, group A, member 1; NUR77; orphan nuclear receptor HMR; orphan nuclear receptor TR3; ST-59; steroid receptor TR3; testicular receptor 3; TR3; TR3 orphan receptor
Orthologs:
Mus musculus (house mouse) : Nr4a1 (nuclear receptor subfamily 4, group A, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr4a1 (nuclear receptor subfamily 4, group A, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Canis lupus familiaris (dog) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,022,832 - 52,059,507 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371252,416,616 - 52,453,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,731,458 - 50,739,554 (+)NCBINCBI36hg18NCBI36
Build 341250,723,762 - 50,736,019NCBI
Celera1251,247,867 - 51,255,961 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1249,449,770 - 49,486,519 (+)NCBIHuRef
CHM1_11252,382,884 - 52,419,560 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NR4A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732751
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.