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Gene: Vps45 (vacuolar protein sorting 45) Mus musculus
Symbol: Vps45
Name: vacuolar protein sorting 45
Description: Predicted to be involved in protein transport and vesicle docking involved in exocytosis. Localizes to Golgi membrane and endosome membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI462172; AW554165; mVps45; vacuolar protein sorting 45 (yeast); vacuolar protein sorting protein 45; vacuolar protein sorting-associated protein 45
Homo sapiens (human) : VPS45 (vacuolar protein sorting 45 homolog)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vps45 (vacuolar protein sorting 45 homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vps45 (vacuolar protein sorting 45 homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : VPS45 (vacuolar protein sorting 45 homolog)
Canis lupus familiaris (dog) : VPS45 (vacuolar protein sorting 45 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vps45 (vacuolar protein sorting 45 homolog)
Sus scrofa (pig) : VPS45 (vacuolar protein sorting 45 homolog)
Chlorocebus sabaeus (African green monkey) : VPS45 (vacuolar protein sorting 45 homolog)
Heterocephalus glaber (naked mole-rat) : Vps45 (vacuolar protein sorting 45 homolog)
more info ...
Related Pseudogenes: Gm13494  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl395,999,832 - 96,058,466 (-)EnsemblGRCm38mm10GRCm38
GRCm38395,999,832 - 96,059,661 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37395,803,755 - 95,862,378 (-)NCBIGRCm37mm9NCBIm37
MGSCv36396,085,265 - 96,143,860 (-)NCBImm8
Celera397,433,896 - 97,493,930 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Vps45
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732755
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.