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Gene: Chrnb4 (cholinergic receptor, nicotinic, beta polypeptide 4) Mus musculus
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Symbol: Chrnb4
Name: cholinergic receptor, nicotinic, beta polypeptide 4
Description: Exhibits transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to acetylcholine binding activity and acetylcholine receptor activity. Involved in several processes, including behavioral response to nicotine; positive regulation of transmission of nerve impulse; and synaptic transmission involved in micturition. Localizes to cholinergic synapse. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and thymus. Orthologous to human CHRNB4 (cholinergic receptor nicotinic beta 4 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; 4,4'-sulfonyldiphenol; benzalkonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acrb-4; Acrb4; neuronal acetylcholine receptor subunit beta-4; nicotinic acetylcholine receptor beta4 subunit
Orthologs:
Homo sapiens (human) : CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Chrnb4 (cholinergic receptor nicotinic beta 4 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrnb4 (cholinergic receptor nicotinic beta 4 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)
Canis lupus familiaris (dog) : CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrnb4 (cholinergic receptor nicotinic beta 4 subunit)
Sus scrofa (pig) : CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)
Heterocephalus glaber (naked mole-rat) : Chrnb4 (cholinergic receptor nicotinic beta 4 subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl955,028,154 - 55,048,779 (-)EnsemblGRCm38mm10GRCm38
GRCm38955,028,154 - 55,048,953 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37954,875,963 - 54,896,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv36954,826,293 - 54,846,681 (-)NCBImm8
Celera952,271,558 - 52,291,872 (-)NCBICelera
Cytogenetic Map9BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Chrnb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732765
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.