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Gene: GNB1 (G protein subunit beta 1) Homo sapiens
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Symbol: GNB1
Name: G protein subunit beta 1
Description: Exhibits GTPase activity and GTPase binding activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and cellular response to prostaglandin E stimulus. Localizes to the heterotrimeric G-protein complex. Implicated in autosomal dominant non-syndromic intellectual disability 42 and precursor lymphoblastic lymphoma/leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta subunit, signal-transducing proteins GS/GI; G protein, beta-1 subunit; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide binding protein, beta 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; MRD42; testicular tissue protein Li 72; transducin beta chain 1
Orthologs:
Mus musculus (house mouse) : Gnb1 (guanine nucleotide binding protein (G protein), beta 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnb1 (G protein subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb1 (G protein subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB1 (G protein subunit beta 1)
Canis lupus familiaris (dog) : GNB1 (G protein subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb1 (G protein subunit beta 1)
Sus scrofa (pig) : GNB1 (G protein subunit beta 1)
Chlorocebus sabaeus (African green monkey) : GNB1 (G protein subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Gnb1 (G protein subunit beta 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11,785,285 - 1,891,117 (-)EnsemblGRCh38hg38GRCh38
GRCh3811,785,285 - 1,891,117 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711,716,725 - 1,822,552 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,706,589 - 1,812,355 (-)NCBINCBI36hg18NCBI36
Build 3411,748,891 - 1,854,657NCBI
Celera1824,442 - 878,396 (+)NCBI
Cytogenetic Map1p36.33NCBI
HuRef1993,370 - 1,099,481 (-)NCBIHuRef
CHM1_111,703,767 - 1,809,575 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on GNB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732785
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.