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Gene: PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) Homo sapiens
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Symbol: PFKFB1
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
CRRD ID: 732809
Description: Exhibits fructose-2,6-bisphosphate 2-phosphatase activity and identical protein binding activity. Involved in fructose 2,6-bisphosphate metabolic process. Localizes to 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; 6PF-2-K/Fru-2,6-P2ASE liver isozyme; F6PK; fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase; HL2K; MGC116715; MGC116717; PFK/FBPase 1; PFRX
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX54,932,961 - 54,998,534 (-)EnsemblGRCh38hg38GRCh38
GRCh38X54,932,961 - 55,000,052 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X54,959,307 - 55,025,244 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,976,315 - 55,037,236 (-)NCBINCBI36hg18NCBI36
Build 34X54,842,610 - 54,903,532NCBI
CeleraX58,794,738 - 58,855,654 (-)NCBI
Cytogenetic MapXp11.21NCBI
HuRefX52,011,285 - 52,075,912 (-)NCBIHuRef
CHM1_1X54,949,616 - 55,015,006 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PFKFB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732809
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.